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Other Research at Our Lab
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- In collaboration with Robert B. Russell
(EMBL, Heidelberg), we have studied the conservation of exonic
structure in absence of sequence conservation (Betts et al,
2001).
- In collaboration with Timothy M. Thomson
(Hospital de La Vall d'Hebron, Barcelona), we discovered a gene
fusion phenomenon (Thomson et al, 2000).
- In collaboration with Temple F. Smith
(Boston University) and
Ilya Muchnick (Rutger University), we developed a methodology
to reconstruct species phylogenies from a set of partially
inconsistent gene trees (Guigó et al, 1996).
- M.J. Betts, R. Guigó, P. Agarwal and R.B. Russell.
"Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution ?"
EMBO Journal 20(19):5354-5360 (2001) [Abstract]
- T. Thomson, J.J. Lozano, R. Carrió, F. Serras, N. Loukili, M. Valeri, B. Cormand, M.P. del Río, J.F. Abril, M. Burset, E. Sancho, J. Merino, A. Macaya, M. Corominas and R. Guigó.
"Fusion of the human gene for the polyubiquitination co-effector uev-1 with kua, a newly identified gene."
Genome Research 10(11):1743-1756 (2000) [Abstract]
- J.J. Lozano, E. López de Briñas, N.B. Centeno, R. Guigó, and F. Sanz.
"Three-dimensional modeling of human cytochrome p450 1a2 and its interaction with caffeine and carcinogenic aromatic amines."
Journal of Computer Aided Molecular Design, 11(4):395-408 (1997) [Link]
- R. Guigó, I. Muchnik, and T.F. Smith.
"Reconstruction of ancient molecular phylogeny."
Molecular Phylogenetics and Evolution, 6:189-213 (1996) [Abstract]
- E. López de Briñas, J.J. Lozano, R. Guigó, F. Manaut and F. Sanz.
"Secondary structure Prediction. A tool in the alignment of cytochrome P450 1A2 sequence with those of cytochromes P450 CAM, P450 BM3, and P450 TERP."
In F. Sanz, J. Giraldo, F. Manaut, editors:
QSAR and Molecular Modelling: Concepts, Computational Tools and Biological Applications. Pp:601-604.
J.R. Prous Science Publisher, Barcelona, 1995.
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