Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
RID: 1012331716-29817-13686
Query= embl:HS3112010 U31120 Human interleukin-13 (IL-13)
precursor gene, complete cds.
(5670 letters)
Database: Non-redundant SwissProt sequences
104,166 sequences; 38,025,691 total letters
If you have any problems or questions with the results of this search
please refer to the BLAST FAQs
Taxonomy reports
Score E
Sequences producing significant alignments: (bits) Value
gi|462408|sp|P35225|IL13_HUMAN Interleukin-13 precursor (IL... 80 3e-14
gi|7387804|sp|Q9XSV9|IL13_BOVIN INTERLEUKIN-13 PRECURSOR (I... 63 5e-09
gi|1170528|sp|P42203|IL13_RAT INTERLEUKIN-13 PRECURSOR (IL-... 57 3e-07
gi|129377|sp|P20109|IL13_MOUSE INTERLEUKIN-13 PRECURSOR (IL... 53 7e-06
gi|2507155|sp|P37370|VRP1_YEAST VERPROLIN 33 0.85
gi|13634073|sp|O88799|ZAN_MOUSE ZONADHESIN PRECURSOR 34 2.4
gi|5921169|sp|O15265|ATX7_HUMAN ATAXIN 7 (SPINOCEREBELLAR A... 33 5.4
gi|399170|sp|P30754|CAFF_RIFPA FIBRIL-FORMING COLLAGEN ALPH... 33 5.4
gi|120820|sp|P03337|GAG_FSVGA GAG polyprotein [Contains: Co... 33 5.4
gi|128127|sp|P19246|NFH_MOUSE NEUROFILAMENT TRIPLET H PROTE... 33 7.0
gi|120822|sp|P04322|GAG_FSVHZ GAG polyprotein [Contains: Co... 32 9.1
gi|417175|sp|Q02362|ICP4_HSVMG TRANS-ACTING TRANSCRIPTIONAL... 32 9.1
gi|728996|sp|P39059|CA1E_HUMAN Collagen alpha 1(XV) chain p... 32 9.1
Alignments
>gi|462408|sp|P35225|IL13_HUMAN Interleukin-13 precursor (IL-13)
Length = 132
Score = 80.5 bits (197), Expect = 3e-14
Identities = 39/39 (100%), Positives = 39/39 (100%)
Frame = +3
Query: 2229 TTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQK 2345
TTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQK
Sbjct: 6 TTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQK 44
Score = 75.5 bits (184), Expect = 9e-13
Identities = 35/42 (83%), Positives = 38/42 (90%)
Frame = +1
Query: 3688 LGVPSPQYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAG 3813
+ + + YCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAG
Sbjct: 56 INLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAG 97
Score = 72.4 bits (176), Expect = 8e-12
Identities = 35/35 (100%), Positives = 35/35 (100%)
Frame = +2
Query: 4160 QFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGRFN 4264
QFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGRFN
Sbjct: 98 QFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGRFN 132
Score = 45.4 bits (106), Expect = 0.001
Identities = 20/27 (74%), Positives = 23/27 (85%)
Frame = +1
Query: 3376 LLTVTLLPQAPLCNGSMVWSINLTAGM 3456
L+ +T +APLCNGSMVWSINLTAGM
Sbjct: 36 LVNITQNQKAPLCNGSMVWSINLTAGM 62
>gi|7387804|sp|Q9XSV9|IL13_BOVIN INTERLEUKIN-13 PRECURSOR (IL-13)
Length = 132
Score = 63.2 bits (152), Expect = 5e-09
Identities = 30/40 (75%), Positives = 32/40 (80%)
Frame = +3
Query: 2229 TTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQKV 2348
T VI L C GG SP PVP +TAL+ELIEELVNITQNQKV
Sbjct: 6 TAVIVLICFGGLTSPSPVPSATALKELIEELVNITQNQKV 45
Score = 55.1 bits (131), Expect = 1e-06
Identities = 23/41 (56%), Positives = 32/41 (77%)
Frame = +1
Query: 3688 LGVPSPQYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSA 3810
L + S YCAAL+SLI++S CS I++T++ML+ CPHK SA
Sbjct: 56 LNLTSSMYCAALDSLISISNCSVIQRTKKMLNALCPHKPSA 96
Score = 48.9 bits (115), Expect = 9e-05
Identities = 24/36 (66%), Positives = 29/36 (79%)
Frame = +2
Query: 4157 QQFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGRFN 4264
+Q SS +VRDTKIEVAQF+KDLL H + +FR RFN
Sbjct: 97 KQVSSEYVRDTKIEVAQFLKDLLRHSRIVFRNERFN 132
Score = 39.7 bits (91), Expect = 0.057
Identities = 16/27 (59%), Positives = 21/27 (77%)
Frame = +1
Query: 3376 LLTVTLLPQAPLCNGSMVWSINLTAGM 3456
L+ +T + PLCNGSMVWS+NLT+ M
Sbjct: 36 LVNITQNQKVPLCNGSMVWSLNLTSSM 62
>gi|1170528|sp|P42203|IL13_RAT INTERLEUKIN-13 PRECURSOR (IL-13) (T-CELL ACTIVATION PROTEIN P600)
Length = 131
Score = 57.4 bits (137), Expect = 3e-07
Identities = 30/46 (65%), Positives = 34/46 (73%), Gaps = 4/46 (8%)
Frame = +3
Query: 2229 TTVIALTCLGGFASPGPV----PPSTALRELIEELVNITQNQKVSV 2354
T V+AL CLGG A+PGPV P ALRELIEEL NITQ+QK S+
Sbjct: 6 TAVLALACLGGLATPGPVRRSTSPPVALRELIEELSNITQDQKTSL 51
Score = 47.8 bits (112), Expect = 2e-04
Identities = 20/33 (60%), Positives = 26/33 (78%)
Frame = +1
Query: 3709 YCAALESLINVSGCSAIEKTQRMLSGFCPHKVS 3807
+CAALESL N+S C+AI +TQR+L+G C K S
Sbjct: 67 FCAALESLTNISSCNAIHRTQRILNGLCNQKAS 99
Score = 33.9 bits (76), Expect = 3.1
Identities = 16/24 (66%), Positives = 19/24 (78%)
Frame = +2
Query: 4184 DTKIEVAQFVKDLLLHLKKLFREG 4255
DTKIEVAQF+ LL + K+LFR G
Sbjct: 107 DTKIEVAQFISKLLNYSKQLFRYG 130
Score = 32.7 bits (73), Expect = 7.0
Identities = 14/26 (53%), Positives = 18/26 (68%)
Frame = +1
Query: 3376 LLTVTLLPQAPLCNGSMVWSINLTAG 3453
L +T + LCN SMVWS++LTAG
Sbjct: 40 LSNITQDQKTSLCNSSMVWSVDLTAG 65
>gi|129377|sp|P20109|IL13_MOUSE INTERLEUKIN-13 PRECURSOR (IL-13) (T-CELL ACTIVATION PROTEIN P600)
Length = 131
Score = 52.8 bits (125), Expect = 7e-06
Identities = 27/42 (64%), Positives = 32/42 (75%), Gaps = 4/42 (9%)
Frame = +3
Query: 2229 TTVIALTCLGGFASPGPVPPSTA----LRELIEELVNITQNQ 2342
T V+AL CLGG A+PGPVP S + L+ELIEEL NITQ+Q
Sbjct: 6 TAVLALACLGGLAAPGPVPRSVSLPLTLKELIEELSNITQDQ 47
Score = 42.4 bits (98), Expect = 0.009
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +1
Query: 3709 YCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGV 3816
+C AL+SL N+S C+AI +TQR+L G C K V
Sbjct: 66 FCVALDSLTNISNCNAIYRTQRILHGLCNRKAPTTV 101
Score = 36.6 bits (83), Expect = 0.48
Identities = 14/18 (77%), Positives = 16/18 (88%)
Frame = +1
Query: 3400 QAPLCNGSMVWSINLTAG 3453
Q PLCNGSMVWS++L AG
Sbjct: 47 QTPLCNGSMVWSVDLAAG 64
Score = 34.7 bits (78), Expect = 1.8
Identities = 16/26 (61%), Positives = 19/26 (72%)
Frame = +2
Query: 4184 DTKIEVAQFVKDLLLHLKKLFREGRF 4261
DTKIEVA F+ LL + K+LFR G F
Sbjct: 106 DTKIEVAHFITKLLSYTKQLFRHGPF 131
>gi|2507155|sp|P37370|VRP1_YEAST VERPROLIN
Length = 817
Score = 32.7 bits (73), Expect(2) = 0.85
Identities = 26/94 (27%), Positives = 38/94 (39%), Gaps = 4/94 (4%)
Frame = -1
Query: 1023 PYPLPPRTSASPGPLSACSG----SLRPVLDGAQPPHKGVLVTLLTRHAGFPLRGIPGLP 856
P P+ P + A P PLS S RP + +P H+ + + P P LP
Sbjct: 167 PIPIVPSSPAPPLPLSGASAPKVPQNRPHMPSVRPAHRS--HQRKSSNISLPSVSAPPLP 224
Query: 855 TLSSHRERHSHPLCPHSKLPSPAAGSDSQKSAPS 754
+ S + P P P+P G DS+ P+
Sbjct: 225 SASLPTHVSNPPQAPPPP-PTPTIGLDSKNIKPT 257
Score = 21.6 bits (44), Expect(2) = 0.85
Identities = 9/18 (50%), Positives = 12/18 (66%)
Frame = -3
Query: 1156 AAPGLGPTAMSPFPALPS 1103
AAP + +SP PA+PS
Sbjct: 131 AAPPIPNAPLSPAPAVPS 148
>gi|13634073|sp|O88799|ZAN_MOUSE ZONADHESIN PRECURSOR
Length = 5376
Score = 34.3 bits (77), Expect = 2.4
Identities = 38/143 (26%), Positives = 54/143 (37%), Gaps = 10/143 (6%)
Frame = +3
Query: 1740 AGRLWSQPQCTKTICSALLVTQKGLRTGAQSWVSCPGTQGCH-----RQNCWNSGQHCKC 1904
AG+ W+ P CT++ C+ + G QS PGT C NC C
Sbjct: 3487 AGKTWTSPGCTQS-CACM-----GGAVQCQSSQCPPGTY-CKDNEDGNSNCAKITLQCPA 3539
Query: 1905 HAALR---APCLPLELNPPRSWKLCPGPFSISP*EIKLFPLCDTGFSTK*NQD--E*RCG 2069
H+ PCLP L+P LC G P K +C +G+ N+ RCG
Sbjct: 3540 HSLFTNCLPPCLPSCLDPD---GLCKGASPKVPSTCKEGCICQSGYVLSNNKCLLRNRCG 3596
Query: 2070 F*IVPEKAETMVSGVTTWAYKSC 2138
+ ++ TW + C
Sbjct: 3597 ---CKDAHGALIPEDKTWVSRGC 3616
>gi|5921169|sp|O15265|ATX7_HUMAN ATAXIN 7 (SPINOCEREBELLAR ATAXIA TYPE 7 PROTEIN)
Length = 892
Score = 33.1 bits (74), Expect = 5.4
Identities = 27/108 (25%), Positives = 38/108 (35%), Gaps = 2/108 (1%)
Frame = -1
Query: 1023 PYPLPPRTSASP--GPLSACSGSLRPVLDGAQPPHKGVLVTLLTRHAGFPLRGIPGLPTL 850
P+P PPRTS P P +P + PH L R G P + P
Sbjct: 414 PHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPH----TPSLPRPPGCPAQQGGSAPID 469
Query: 849 SSHRERHSHPLCPHSKLPSPAAGSDSQKSAPSLEGPQCLECRYLAARP 706
HP P ++ P+ S+ + E + L+C Y P
Sbjct: 470 PPPVHESPHPPLPATE-PASRLSSEEGEGDDKEESVEKLDCHYSGHHP 516
>gi|399170|sp|P30754|CAFF_RIFPA FIBRIL-FORMING COLLAGEN ALPHA CHAIN
Length = 1027
Score = 33.1 bits (74), Expect = 5.4
Identities = 16/45 (35%), Positives = 24/45 (52%), Gaps = 2/45 (4%)
Frame = +3
Query: 2427 PGPKMPVGQEKSPWTKARPSHEGERSWAG--GLSTVDGPMEVSGR 2555
PGP P+G SP P +G+R +G G + GP+ +SG+
Sbjct: 162 PGPPGPIGSTGSPGFPGTPGSKGDRGQSGIXGAQGLQGPVGLSGQ 206
>gi|120820|sp|P03337|GAG_FSVGA GAG polyprotein [Contains: Core protein P15; Core protein P12; Core
protein P30]
Length = 425
Score = 33.1 bits (74), Expect = 5.4
Identities = 39/125 (31%), Positives = 49/125 (39%), Gaps = 11/125 (8%)
Frame = -1
Query: 1029 FLPYPLPPRT---SASPGPLSACSGSLRPVLDGAQPPHKGV--------LVTLLTRHAGF 883
FLP P PP + SP P + + SL PVL + PP V L+ LLT
Sbjct: 177 FLPPPKPPTSLPQPLSPQPSAPLTSSLYPVLPKSDPPKPPVLPPDPSSPLIDLLTEEPP- 235
Query: 882 PLRGIPGLPTLSSHRERHSHPLCPHSKLPSPAAGSDSQKSAPSLEGPQCLECRYLAARPL 703
P G G P S R + P+ + +SQ + P EGP RP
Sbjct: 236 PYPGGHG-PPPSGPRTPTASPIASRLRERRENPAEESQ-ALPLREGPN--------NRPQ 285
Query: 702 YGPVS 688
Y P S
Sbjct: 286 YWPFS 290
>gi|128127|sp|P19246|NFH_MOUSE NEUROFILAMENT TRIPLET H PROTEIN (200 KDA NEUROFILAMENT PROTEIN)
(NEUROFILAMENT HEAVY POLYPEPTIDE) (NF-H)
Length = 1087
Score = 32.7 bits (73), Expect = 7.0
Identities = 24/88 (27%), Positives = 37/88 (41%)
Frame = -1
Query: 1011 PPRTSASPGPLSACSGSLRPVLDGAQPPHKGVLVTLLTRHAGFPLRGIPGLPTLSSHRER 832
PP + SP + PV +GA+PP K + + + A P++ +PT E+
Sbjct: 800 PPAEAKSPEKAKS------PVKEGAKPPEKAKPLDVKSPEAQTPVQEEATVPTDIRPPEQ 853
Query: 831 HSHPLCPHSKLPSPAAGSDSQKSAPSLE 748
P +K P S+K AP E
Sbjct: 854 VKSPAKEKAKSPEKEEAKTSEKVAPKKE 881
>gi|120822|sp|P04322|GAG_FSVHZ GAG polyprotein [Contains: Core protein P15; Core protein P12; Core
protein P30]
Length = 414
Score = 32.3 bits (72), Expect = 9.1
Identities = 40/135 (29%), Positives = 48/135 (34%), Gaps = 21/135 (15%)
Frame = -1
Query: 1029 FLPYPLPPRT---SASPGPLSACSGSLRPVLDGAQPPHKGV--------LVTLLTRH--- 892
FLP P PP SP P + + SL PVL PP V L+ LLT
Sbjct: 174 FLPPPKPPTPLPQPLSPQPSAPLTSSLYPVLPKTDPPKPPVLPPDPSSPLIDLLTEEPPP 233
Query: 891 ---AGFPLRGIPGLPT----LSSHRERHSHPLCPHSKLPSPAAGSDSQKSAPSLEGPQCL 733
PL P PT S RER +P ++ ++ P EGP
Sbjct: 234 YPGGHGPLPSGPRTPTASPIASRLRERRENP-------------AEESQALPLREGPN-- 278
Query: 732 ECRYLAARPLYGPVS 688
RP Y P S
Sbjct: 279 ------NRPQYWPFS 287
>gi|417175|sp|Q02362|ICP4_HSVMG TRANS-ACTING TRANSCRIPTIONAL ACTIVATOR PROTEIN ICP4 (IMMEDIATE-EARLY
PROTEIN IE175)
Length = 1415
Score = 32.3 bits (72), Expect = 9.1
Identities = 38/152 (25%), Positives = 56/152 (36%), Gaps = 3/152 (1%)
Frame = -3
Query: 4891 PSPD---PASDEAPRPQDPSEVAEFCTQYLLPGTPGVHCFSAGALSL*TLGSKCQQPQSS 4721
P PD P++D P P +FC P T G + + + L P+SS
Sbjct: 60 PVPDWNNPSTDWRPSPPRSGPKKDFCGDLPAPLTSGPRLTTPSSGRMSELPHTTSSPRSS 119
Query: 4720 PIPNGDKHTHLNNTQ**IRPRRSVPELLSASVACV*SGSLSHHMSGKGGTHCNATVCSRA 4541
P P G + T +N I P R+ P + G +S S + +++ S +
Sbjct: 120 PRPRGPE-TSPSNEHIIISPPRNPPSNTTHRNV----GHVSRSPSSSSSSSSSSSPSSSS 174
Query: 4540 GEGCRDMSSLGPPSSGPWTEEAHQAEPWARGR 4445
SS PS P A + RGR
Sbjct: 175 LIVLSSPSSSRSPSPSPPRPRADSSSRPRRGR 206
>gi|728996|sp|P39059|CA1E_HUMAN Collagen alpha 1(XV) chain precursor
Length = 1388
Score = 32.3 bits (72), Expect = 9.1
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 7/98 (7%)
Frame = +3
Query: 2271 PGPVPPSTALRELIEELVNITQ------NQKVSVG*PG-S*L*GLQGG*FPR*GHEQAGP 2429
PGP P ++ L L+NIT + VG PG L GL G P
Sbjct: 789 PGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGF-----------P 837
Query: 2430 GPKMPVGQEKSPWTKARPSHEGERSWAGGLSTVDGPME 2543
GP+ P G P +GE+ G + T D P+E
Sbjct: 838 GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLE 875
Database: Non-redundant SwissProt sequences
Posted date: Jan 29, 2002 4:08 AM
Number of letters in database: 38,025,691
Number of sequences in database: 104,166
Lambda K H
0.318 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 377,762,412
Number of Sequences: 104166
Number of extensions: 9060296
Number of successful extensions: 28791
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 19340
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28711
length of database: 38,025,691
effective HSP length: 122
effective length of database: 25,317,439
effective search space used: 44735914713
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
