ID HS436531 standard; mRNA; HUM; 3426 BP. XX AC U43653; XX SV U43653.1 XX DT 16-MAR-1996 (Rel. 47, Created) DT 30-JUN-1999 (Rel. 60, Last updated, Version 4) XX DE Human obese protein (ob) mRNA, complete cds. XX KW . XX OS Homo sapiens (human) OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Primates; Catarrhini; Hominidae; Homo. XX RN [1] RP 1-3426 RX MEDLINE; 96223958. RX PUBMED; 8626726. RA Gong D.W., Bi S., Pratley R.E., Weintraub B.D.; RT "Genomic structure and promoter analysis of the human obese gene"; RL J. Biol. Chem. 271(8):3971-3974(1996). XX RN [2] RP 1-3426 RA Gong D.-W.; RT ; RL Submitted (19-DEC-1995) to the EMBL/GenBank/DDBJ databases. RL Da-Wei Gong, Molecular and Cellular Endocrinology Branch, NIDDK/NIH, RL Bldg10/Rm8D14, 10 Center Drive MSC1822, Bethesda, MD 20892, USA XX DR GOA; P41159. DR SWISS-PROT; P41159; OB_HUMAN. XX FH Key Location/Qualifiers FH FT source 1..3426 FT /chromosome="7" FT /db_xref="taxon:9606" FT /mol_type="mRNA" FT /organism="Homo sapiens" FT gene 57..560 FT /gene="ob" FT CDS 57..560 FT /codon_start=1 FT /db_xref="GOA:P41159" FT /db_xref="SWISS-PROT:P41159" FT /gene="ob" FT /product="obese protein" FT /protein_id="AAC50400.1" FT /translation="MHWGTLCGFLWLWPYLFYVQAVPIQKVQDDTKTLIKTIVTRINDI FT SHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNVIQISNDLENL FT RDLLHVLAFSKSCHLPWASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDL FT SPGC" XX SQ Sequence 3426 BP; 887 A; 799 C; 920 G; 820 T; 0 other; gtaggaatcg cagcgccaac ggttgcaagg cccaagaagc catcctggga aggaaaatgc 60 attggggaac cctgtgcgga ttcttgtggc tttggcccta tcttttctat gtccaagctg 120 tgcccatcca aaaagtccaa gatgacacca aaaccctcat caagacaatt gtcaccagga 180 tcaatgacat ttcacacacg cagtcagtct cctccaaaca gaaagtcacc ggtttggact 240 tcattcctgg gctccacccc atcctgacct tatccaagat ggaccagaca ctggcagtct 300 accaacagat cctcaccagt atgccttcca gaaacgtgat ccaaatatcc aacgacctgg 360 agaacctccg ggatcttctt cacgtgctgg ccttctctaa gagctgccac ttgccctggg 420 ccagtggcct ggagaccttg gacagcctgg ggggtgtcct ggaagcttca ggctactcca 480 cagaggtggt ggccctgagc aggctgcagg ggtctctgca ggacatgctg tggcagctgg 540 acctcagccc tgggtgctga ggccttgaag gtcactcttc ctgcaaggac tacgttaagg 600 gaaggaactc tggcttccag gtatctccag gattgaagag cattgcatgg acacccctta 660 tccaggactc tgtcaatttc cctgactcct ctaagccact cttccaaagg cataagaccc 720 taagcctcct tttgcttgaa accaaagata tatacacagg atcctattct caccaggaag 780 ggggtccacc cagcaaagag tgggctgcat ctgggattcc caccaaggtc ttcagccatc 840 aacaagagtt gtcttgtccc ctcttgaccc atctccccct cactgaatgc ctcaatgtga 900 ccaggggtga tttcagagag ggcagagggg taggcagagc ctttggatga ccagaacaag 960 gttccctctg agaattccaa ggagttccat gaagaccaca tccacacacg caggaactcc 1020 cagcaacaca agctggaagc acatgtttat ttattctgca ttttattctg gatggatttg 1080 aagcaaagca ccagcttctc caggctcttt ggggtcagcc agggccaggg gtctccctgg 1140 agtgcagttt ccaatcccat agatgggtct ggctgagctg aacccatttt gagtgactcg 1200 agggttgggt tcatctgagc aagagctggc aaaggtggct ctccagttag ttctctcgta 1260 actggtttca tttctactgt gactgatgtt acatcacagt gtttgcaatg gtgttgccct 1320 gagtggatct ccaaggacca ggttatttta aaaagatttg ttttgtcaag tgtcatatgt 1380 aggtgtctgc acccaggggt ggggaatgtt tgggcagaag ggagaaggat ctagaatgtg 1440 ttttctgaat aacatttgtg tggtgggttc tttggaagga gtgagatcat tttcttatct 1500 tctgcaattg cttaggatgt ttttcatgaa aatagctctt tcaggggggt tgtgaggcct 1560 ggccaggcac cccctggaga gaagtttctg gccctggctg accccaaaga gcctggagaa 1620 gctgatgctt tgcttcaaat ccatccagaa taaaacgcaa agggctgaaa gccatttgtt 1680 ggggcagtgg taagctctgg ctttctccga ctgctaggga gtggtctttc ctatcatgga 1740 gtgacggtcc cacactggtg actgcgatct tcagagcagg ggtccttggt gtgaccctct 1800 gaatgggtcc agggttgatc acactctggg tttattacat ggcagtgttc ctatttgggg 1860 cttgcatgcc aaattgtagt tcttgtctga ttggctcacc caagcaaggc caaaattacc 1920 aaaaatcttg gggggttttt actccagtgg tgaagaaaac tcctttagca ggtggtcctg 1980 agacctgaca agcactgcta ggcgagtgcc aggactcccc aggccaggcc accaggatgc 2040 ccttcccact ggaggtcaca ttcaggaaga tgaaagagga ggtttggggt ctgccaccat 2100 cctgctgctg tgtttttgct atcacacagt gggtggtgga tctgtccaag gaaacttgaa 2160 tcaaagcagt taactttaag actgagcacc tgcttcatgc tcagccctga ctggtgctat 2220 aggctggaga agctcaccca ataaacatta agattgaggc ctgccctcag ggatcttgcg 2280 ttcccagtgg tcaaaccgca ctcacccatg tgccaaggtg gggtatttac cacagcagct 2340 gaacagccaa atgcatggtg cagttgacag caggtgggaa atggtatgag ctgagggggg 2400 ccgtgcccag gggcccacag ggaaccctgc ttgcactttg taacatgttt acttttcagg 2460 gcatcttagc ttctattata gccacatccc tttgaaacaa gataactgag aatttaaaaa 2520 taagaaaata cataagacca taacagccaa caggtggcag gaccaggact atagcccagg 2580 tcctctgata cccagagcat tacgtgagcc aggtaatgag ggactggaac cagggagacc 2640 gagcgctttc tggaaaagag gagtttcgag gtagagtttg aaggaggtga gggatgtgaa 2700 ttgcctgcag agagaagcct gttttgttgg aaggtttggt gtgtggagat gcagaggtaa 2760 aagtgtgagc agtgagttac agcgagaggc agagaaagaa gagacaggag ggcaagggcc 2820 atgctgaagg gaccttgaag ggtaaagaag tttgatatta aaggagttaa gagtagcaag 2880 ttctagagaa gaggctggtg ctgtggccag ggtgagagct gctctggaaa atgtgaccca 2940 gatcctcaca accacctaat caggctgagg tgtcttaagc cttttgctca caaaacctgg 3000 cacaatggct aattcccaga gtgtgaaact tcctaagtat aaatggttgt ctgtttttgt 3060 aacttaaaaa aaaaaaaaaa agtttggccg ggtgcggtgg ctcacgcctg taatcccagc 3120 actttgggag gccaaggtgg ggggatcaca aggtcactag atggcgagca tcctggccaa 3180 catggtgaaa ccccgtctct actaaaaaca caaaagttag ctgagcgtgg tggcgggcgc 3240 ctgtagtccc agccactcgg gaggctgaga caggagaatc gcttaaacct gggaggcgga 3300 gagtacagtg agccaagatc gcgccactgc actccggcct gatgacagag cgagattccg 3360 tcttaaaaaa aaaaaaaaaa aaagtttgtt tttaaaaaaa tctaaataaa ataactttgc 3420 cccctg 3426 //